FORMULATIONS

Phase A: Combine all ingredients of phase A and stir until everything is completely dissolved.
Phase B: Adjust pH to 5 – 6 and add phase B. Heat to 75°C.
Phase C: Combine all ingredients of phase C and heat to 75°C.
Add phase C to phase A/B while stirring.
Phase D: Add phase D under 40 °C and homogenise.
Adjust the pH to 5.5 ± 0.05.

Appearance: White high viscous cream
pH: 5.5 ± 0.05
Stability: No separation after centrifugation (4000 rpm, 30 min), stable for 3 months at room temperature and 40 °C
Microbiological stability: proven

Phase A: Combine all ingredients of phase A and stir until everything is dissolved.
Phase B: Combine all ingredients of phase B and add to phase A under stirring. Stir until everything is dissolved.
Phase C: Add phase C.
Adjust the pH to 5.5 ± 0.05.

Appearance: Transparent, viscous gel
pH: 5.5 ± 0.05
Stability: No separation after centrifugation (4000 rpm, 30 min), stable for 3 months at room temperature and 40 °C
Microbiological stability: proven

Phase A: Combine all ingredients of phase A. Raise the pH to 11 to dissolve Cosphagard® SA natural. When everything is dissolved, lower the pH back to 4-5 again.
Phase B: Combine Glycerin, Cosphaderm® X 34 and Cosphaderm® Sodium Hyaluronate high and stir until the powder is wetted. Then add it to phase A.
Phase C: Add phase C under stirring.
Adjust the pH to 4.0 ± 0.05.

Appearance: Transparent, semi-viscous gel
pH: 4.0 ± 0.05
Stability: No separation after centrifugation (4000 rpm, 30 min), stable for 3 months at room temperature and 40 °C
Microbiological stability: proven

Phase A: Disperse the thickeners in glycerol and Cosphaderm® Propanediol natural.
Phase B: Add demin. water and stir until everything is dissolved.
Phase C: Add phase C to A/B.
Adjust the pH to 5.5 ± 0.05.

Appearance: Translucent, viscous gel
pH: 5.5 ± 0.05
Stability: No separation after centrifugation (4000 rpm, 30 min), stable for 3 months at room temperature and 40 °C
Microbiological stability: proven

Phase A: Combine all ingredients of phase A. Raise the pH to 11 to dissolve Cosphagard® SA natural completely.
Phase B: Add phase B and lower the pH to 4.0 ± 0.05.

Appearance: Clear, liquid solution
pH: 4.0 ± 0.05
Stability: No separation after centrifugation (4000 rpm, 30 min), stable for 3 months at room temperature and 40 °C
Microbiological stability: proven

Phase A: Combine all ingredients of phase A.
Phase B: Prepare phase B and slowly add to phase A under stirring. Continue stirring until everything is completely dissolved.
Adjust pH to 5.5 ± 0.05.

Appearance: Transparent, clear liquid
pH: 5.5 ± 0.05
Stability: No separation after centrifugation (4000 rpm, 30 min), stable for 3 months at room temperature and 40 °C
Microbiological stability: proven

Phase A: Combine all ingredients of phase A and stir until everything is completely dissolved.
Phase B: Combine all ingredients of phase B.
Heat both phases separately to 70-75 °C and add phase B to A while stirring. Then homogenise the formulation.
Phase C: Dissolve Cosphaderm® Magnolia Extract 98 in Cosphaderm® Dicapo natural.
Add phase C and phase D to phase A+B after cooling to 40 °C while stirring. Adjust the pH to 5.5 ± 0.05.

Appearance: Light beige, shiny, fluid emulsion
pH: 5.5 ± 0.05
Stability: No separation after centrifugation (4000 rpm, 30 min), stable for 3 months at room temperature and 40 °C
Microbiological stability: proven

Phase A: Combine all ingredients of phase A under stirring until Cosphaderm® X 34 is completely dissolved.
Phase B: Combine all ingredients of phase B.
Heat both phases separately to 70 °C and add phase B to phase A under stirring.
After stirring homogenise the formulation and adjust the pH to 5.5 ± 0.05.

Appearance: White, shiny, low viscous emulsion
pH: 5.5 ± 0.05
Stability: No separation after centrifugation (4000 rpm, 30 min), stable for 3 months at room temperature and 40 °C
Microbiological stability: proven

Phase A: Combine all ingredients of phase A and stir until everything is completely dissolved.
Phase B: Combine all ingredients of phase B.
Heat both phases separately to 75-80 °C. Add phase B to A while stirring and then homogenise.
Adjust the pH to 5.5 ± 0.05.

Appearance: White, viscous gel cream
pH: 5.5 ± 0.05
Stability: No separation after centrifugation (4000 rpm, 30 min), stable for 3 months at room temperature and 40 °C
Microbiological stability: proven

Phase A: Combine all ingredients of phase A and stir until everything is completely dissolved.
Phase B: Add phase B to A while stirring. Then heat the water phase to 70-75 °C.
Phase C: Combine all ingredients of phase C and heat to 75°C. Phase D is added to the oil phase just before emulsion is formed.
Add phase C+D to the water phase while stirring. Homogenise at 40°C.
Add phase E to the emulsion.
Adjust the pH to 5.5 ± 0.05.

Appearance: Light beige, white cream
pH: 5.5 ± 0.05
Stability: No separation after centrifugation (4000 rpm, 30 min), stable for 3 months at room temperature and 40 °C
Microbiological stability: proven

Phase A: Combine all ingredients of phase A.
Phase B: Disperse Cosphaderm® KG in glycerol and add it to phase A. Stir until completely dissolved.
Phase C: Add phase C and stir until everything is homogeneous.
Phase D: Prepare phase D and melt at 50 °C, then cool down to room temperature.
Add phase D to the water phase and homogenise.
Adjust pH to 5.5 ± 0.05.

Appearance: Shiny, viscous emulsion
pH: 5.5 ± 0.05
Stability: No separation after centrifugation (4000 rpm, 30 min), stable for 3 months at room temperature and 40 °C
Microbiological stability: proven

Phase A: Mix phase A and stir until everything is completely dissolved.
Phase B: Add phase B to phase A and stir until dispersed.
Phase C: Slowly add phase C to phase A+B and stir until complete dissolution.
Phase D: Mix all ingredients of phase D and heat phase A+B+C and D separately to 80 °C.
Add phase D slowly to phase A+B+C while stirring.
Phase E: Add phase E to the finished formulation (below 40 °C).
Adjust the pH to 5.5 ± 0.05.

Appearance: Shiny, fluid emulsion
pH: 5.5 ± 0.05
Stability: No separation after centrifugation (4000 rpm, 30 min), stable for 3 months at room temperature and 40 °C
Microbiological stability: proven

Phase A: Prepare phase A and stir until complete dissolution.
Phase B: Prepare phase B and heat to 50 °C until everything is melted. Let the mixture cool down to room temperature.
Add phase B to phase A and homogenise.
Adjust the pH to 5.5 ± 0.05.

Appearance: White, viscous emulsion
pH: 5.5 ± 0.05
Stability: No separation after centrifugation (4000 rpm, 30 min), stable for 3 months at room temperature and 40 °C
Microbiological stability: proven

Phase A: Combine all ingredients of phase A.
Phase B: Prepare phase B and slowly add to phase A under stirring. Continue stirring until everything is completely dissolved.
Adjust pH to 5.5 ± 0.05.

Appearance: Transparent, low viscous serum
pH: 5.5 ± 0.05
Stability: No separation after centrifugation (4000 rpm, 30 min), stable for 3 months at room temperature and 40 °C
Microbiological stability: proven

Phase A: Combine all ingredients.
Phase B: Prepare phase B and slowly add to phase A under stirring. Continue stirring until everything is completely dissolved.
Adjust pH to 6.5 ± 0.05 if necessary.

Appearance: Translucent, low viscous serum
pH: 6.5 ± 0.05
Stability: No separation after centrifugation (4000 rpm, 30 min), stable for 3 months at room temperature and 40 °C
Microbiological stability: proven

Phase A: Prepare phase A.
Phase B: Pre-disperse phase B and add to the water phase while stirring. Stir until everything is completely dissolved.
Adjust the pH to 5.5 – 6.0 ± 0.05.
Heat the mixture to its boiling point and keep this temperature for 2 – 3 minutes.
Quickly pour the hot mixture into a casting mould and let it cool.

Appearance: Transparent or coloured, elastic jelly patch
pH: 5.5 – 6.0 ± 0.05
Stability: Stable for 3 months at room temperature and 40 °C
Microbiological stability: proven

Phase A: Combine all ingredients of phase A and stir until complete dissolution.
Adjust the pH value to 5.5 ± 0.05.
Phase B: Prepare phase B in a separate beaker.
Add phase B to phase A without stirring and pour mixture into spray flask.

Appearance: Liquid two-phase system with oil phase on top of transparent water phase
pH: 5.5 ± 0.05
Stability: Stable for 3 months at room temperature and 40 °C
Microbiological stability: proven

Phase A: Combine all ingredients of phase A and stir until everything is completely dissolved.
Phase B: Slowly add phase B to A while stirring.
Phase C: Mix all ingredients of phase C and add to phase A+B while stirring.
Adjust the pH to 5.0 ± 0.05.

Appearance: Transparent, low viscous serum
pH: 5.0 ± 0.05
Stability: No separation after centrifugation (4000 rpm, 30 min), stable for 3 months at room temperature and 40 °C
Microbiological stability: proven

Phase A: Combine all ingredients and dissolve Phase A at 40°C.
Phase B: Add phase B to phase A and adjust the pH to 5.0 – 5.5.
Phase C: Add phase C to phase A/B under soft stirring.
Phase D: Dissolve Cosphaderm® Magnolia Extract 98 in Cosphaderm® Propanediol natural and Cosphaderm® TOM. Add phase D to phase A/B/C under stirring.
Adjust the pH to 5.0 ± 0.05.

Appearance: Yellowish, translucent gel
pH: 5.0 ± 0.05
Stability: No separation after centrifugation (4000 rpm, 30 min), stable for 3 months at room temperature and 40 °C
Microbiological stability: proven

Phase A: Combine all ingredients of phase A and stir until everything is dissolved.
Phase B: Slowly add phase B to phase A under stirring. Stir until complete dissolution.
Adjust pH to 5.5 ± 0.05 and heat phase A and B to 70 °C.
Phase C: Combine all ingredients and heat phase C to 70 °C. Add then phase C to phase A and B under strong stirring and homogenise the formulation.
Adjust pH to 5.2 ± 0.05.

Appearance: Slightly yellowish gel cream
pH: 5.2 ± 0.05
Stability: No separation after centrifugation (4000 rpm, 30 min), stable for 3 months at room temperature and 40 °C
Microbiological stability: proven

Phase A: Combine all ingredients of phase A.
Phase B: Add phase B to phase A while stirring and stir until everything is completely dissolved.
Phase C: Prepare phase C and add to phase A+B under slow stirring to prevent foaming.
Adjust pH to 5.5 ± 0.05.

Appearance: Transparent, viscous gel
pH: 5.5 ± 0.05
Stability: No separation after centrifugation (4000 rpm, 30 min), stable for 3 months at room temperature and 40 °C
Microbiological stability: proven

Phase A: Combine all ingredients of phase A.
Phase B: Add phase B to phase A while stirring and stir until everything is completely dissolved.
Phase C: Prepare phase C and add to phase A+B under slow stirring to prevent foaming.
Adjust pH to 5.5 ± 0.05.

Appearance: Transparent, viscous gel
pH: 5.5 ± 0.05
Stability: No separation after centrifugation (4000 rpm, 30 min), stable for 3 months at room temperature and 40 °C
Microbiological stability: proven

Phase A: Combine all ingredients of phase A and stir until everything is completely dissolved.
Phase B: Combine all ingredients of phase B.
Heat both phases separately to 70-75 °C and add phase B to A while homogenising.
Phase C: Dissolve Cosphaderm® Magnolia Extract 98 in Cosphaderm® Diols. Add phase C to phase A/B under stirring.
Adjust the pH to 4.0 ± 0.05.

Appearance: Beige, viscous gel cream
pH: 4.0 ± 0.05
Stability: No separation after centrifugation (4000 rpm, 30 min), stable for 3 months at room temperature and 40 °C
Microbiological stability: proven

Phase A: Combine all ingredients of phase A.
Phase B: Disperse Cosphaderm® KG in glycerol and add phase B to phase A. Stir until everything is dissolved.
Phase C: Add phase B to phase A/B.
Adjust the pH to 4.8 – 5.0.

Appearance: Turbid, high viscous gel
pH: 4.8 – 5.0
Stability: No separation after centrifugation (4000 rpm, 30 min), stable for 3 months at room temperature and 40 °C
Microbiological stability: proven

Phase A: Disperse Cosphaderm® X 34 in glycerol and add demin. water. Stir until everything is dissolved.
Phase B: Add phase B to phase A.
Adjust the pH to 4.8 – 5.0.

Appearance: Transparent, high viscous gel
pH: 4.8 – 5.0
Stability: No separation after centrifugation (4000 rpm, 30 min), stable for 3 months at room temperature and 40 °C
Microbiological stability: proven

Phase A: Combine all ingredients of phase A.
Phase B: Add phase B to A carefully to avoid foaming.
Adjust the pH to 5.5 ± 0.05.

Appearance: Transparent liquid solution
pH: 5.5 ± 0.05
Stability: No separation after centrifugation (4000 rpm, 30 min), stable for 3 months at room temperature and 40 °C
Microbiological stability: proven

Phase A: Combine all ingredients of phase A and stir until everything is dissolved.
Phase B: Add phase B to phase A under stirring.
Phase C: Combine all ingredients of phase C separately. Add then phase C to phase A and B under stirring.
Adjust pH to 5.5 ± 0.05.

Appearance: Transparent liquid solution
pH: 5.5 ± 0.05
Stability: No separation after centrifugation (4000 rpm, 30 min), stable for 3 months at room temperature and 40 °C
Microbiological stability: proven

Phase A: Combine water and Cosphagard® SA natural and raise the pH value to 10 – 11. Stir until complete dissolution. Afterwards lower the pH to approximately 6.
Phase B: Add phase B to phase A and stir until everything is completely dissolved. Heat to 70 °C.
Phase C: Combine all ingredients of phase C and heat to 70 °C.
Add phase C to A+B while stirring. Homogenise at 40°C.
Phase D: Add Cosphaderm® TOM to the emulsion.
Adjust pH to 6.0 ± 0.05.

Appearance: Light beige lotion
pH: 6.0 ± 0.05
Stability: No separation after centrifugation (4000 rpm, 30 min), stable for 3 months at room temperature and 40 °C
Microbiological stability: proven

Phase A: Mix all ingredients except Cosphaderm® CHA. Add Cosphaderm® CHA and Stir phase A until complete dissolution.
Phase B: Slowly add Cosphaderm® X 34 to phase A while stirring.
Phase C: Mix phase C and add to phase A+B while carefully stirring to prevent foaming.
Adjust the pH to 5.5 ± 0.05.

Appearance: Transparent viscous gel
pH: 5.5 ± 0.05
Stability: No separation after centrifugation (4000 rpm, 30 min), stable for 3 months at room temperature and 40 °C
Microbiological stability: proven

Phase A: Prepare phase A and stir until dispersed.
Phase B: Slowly add the water to phase A under stirring and stir until complete dissolution.
If wanted, add heat-proof colour.
Phase C: Prepare phase C, adjust the pH to 5.5 ± 0.05 and set aside.
Heat phase A+B to its boiling point and keep this temperature for 2 – 3 min.
Add phase C to the hot phase A+B. Continue stirring until everything is combined.
Quickly pour the warm mixture into moulds and let it cool down.

Appearance: Clear, solid, elastic jelly
pH: 5.5 – 6.5
Stability: stable for 3 months at room temperature and 40 °C
Microbiological stability: proven

Phase A: Combine all ingredients and stir until Cosphaderm® X 34 is completely dissolved.
Phase B: Combine phase B and add phase B to phase A under slow stirring.
Phase C: Add phase C to phase A+B to thicken the formulation.
Adjust the pH to 5.5 ± 0.05.

Appearance: Milky, white vicous gel
pH: 5.5 ± 0.05
Stability: No separation after centrifugation (4000 rpm, 30 min), stable for 3 months at room temperature and 40 °C
Microbiological stability: proven

Phase A: Dissolve Phase A at 40°C.
Phase B: Combine all ingredients of phase B. Add Phase B to A under stirring.
Phase C: Add all ingredients one by one under moderate speed.
Add phase D to thicken the formulation.
Adjust the pH to 5.5 ± 0.05.

Appearance: Slightly yellow, transparent visocus gel
pH: 5.5 ± 0.05
Stability: No separation after centrifugation (4000 rpm, 30 min), stable for 3 months at room temperature and 40 °C
Microbiological stability: proven

Phase A: Combine all ingredients of phase A and stir until everything is completely dissolved.
Phase B: Add phase B to A carefully to avoid foaming.
Adjust the pH to 5.5 ± 0.05.
Phase C: Add phase C to the final formulation while stirring.

Appearance: Transparent gel with small peeling beads
pH: 5.5 ± 0.05
Stability: No separation after centrifugation (4000 rpm, 30 min), stable for 3 months at room temperature and 40 °C
Microbiological stability: proven

Phase A: Combine ingredients and stir until Cosphaderm® Magnolia Extract 98 is dissolved.
Phase B: Prepare phase B and add to phase A under stirring. Heat the mixture to 50 °C.
Phase C: Slowly add phase C into A+B and stir until complete dissolution.
Phase D: Prepare phase D and add it to phase A+B+C under stirring.
Phase E: Add phase E to the mixture and stir until everything is homogenous.
Phase F: Prepare phase F and add it to the finished formulation.
Adjust the pH to 7.0 ± 0.05.

Appearance: Milky-white paste
pH: 7.0 ± 0.05
Stability: No separation after centrifugation (4000 rpm, 30 min), stable for 3 months at room temperature and 40 °C
Microbiological stability: proven

Phase A: Combine all ingredients of phase A. Pre-dissolve Cosphaderm® X 34 in glycerol and it to phase A. Stir until completely dissolved.
PhaseB: Add phase B to phase A.
Phase C: Pre-dissolve menthol in Cosphaderm® Propanediol natural and then add to phase A+B with the other raw materials.
Phase D: Add phase D and mix homogeneously.
Adjust pH value to 6.8-7.0.

Appearance: Transparent, high viscous gel
pH: 6.8 – 7.0
Stability: No separation after centrifugation (4000 rpm, 30 min), stable for 3 months at room temperature and 40 °C
Microbiological stability: proven

Phase A: Combine all ingredients and stir until everything is completely dissolved.
Phase B: Dissolve the menthol in Cosphaderm® Propanediol natural add phase B to phase A under soft stirring.
Phase C: Add all ingredients of phase C and stir until everything is completely dissolved.
Phase D: Add colour if wanted.
Adjust the pH to 7.0 ± 0.05.

Appearance: Transparent solution
pH: 7.0 ± 0.05
Stability: No separation after centrifugation (4000 rpm, 30 min), stable for 3 months at room temperature and 40 °C
Microbiological stability: proven

Phase A: Combine all ingredients of phase A. Slowly add Cosphaderm® X 34 to phase A and stir until completely dissolved.
Phase B: Combine all ingredients of phase B.
Heat both phases separately to 80-85 °C.
Add phase B to phase A under strong stirring and homogenise the formulation.
Adjust pH to 5.5 ± 0.05.

Appearance: Shiny, off-white high viscous cream
pH: 5.5 ± 0.05
Stability: No separation after centrifugation (4000 rpm, 30 min), stable for 3 months at room temperature and 40 °C
Microbiological stability: proven

Phase A: Combine all ingredients of phase A and stir until everything is completely dissolved.
Phase B: Combine all ingredients of phase B.
Heat both phases separately to 75 °C and add phase B to A while stirring very fast. Homogenise.
Adjust the pH to 5.0 ± 0.05.

Appearance: White viscous lotion
pH: 5.0 ± 0.05
Stability: No separation after centrifugation (4000 rpm, 30 min), stable for 3 months at room temperature and 40 °C
Microbiological stability: proven

Phase A: Combine all ingredients of phase A and stir until completely dissolved.
Phase B: Prepare phase B and separately heat phase A and phase B to 80 °C. Add phase B to phase A while stirring.
Phase C+D: Add phase C and D below 40 °C. Homogenise.
Adjust pH to 5.5 ± 0.05.

Appearance: Slightly yellowish, viscous cream
pH: 5.5 ± 0.05
Stability: No separation after centrifugation (4000 rpm, 30 min), stable for 3 months at room temperature and 40 °C
Microbiological stability: proven

Phase A: Prepare phase A. Raise the pH to 10 to dissolve Cosphaderm® pAS natural and stir until everything is completely dissolved. Afterwards, adjust the pH to 5.5 ± 0.05 by adding Citric Acid.
Phase B: Add all ingredients of phase B to phase A. Then heat phase A+B to 75 °C.
Phase C: Combine all ingredients and heat to 75 °C. Add then phase C to phase A+B under strong stirring and homogenise.
Phase D: Dissolve menthol in ethanol and add phase D below 40°C.
Adjust the pH to 5.5 ± 0.05.

Appearance: White viscous emulsion
pH: 5.5 ± 0.05
Stability: No separation after centrifugation (4000 rpm, 30 min), stable for 3 months at room temperature and 40 °C
Microbiological stability: proven

Phase A: Combine all ingredients of phase A. Stir until everything is completely dissolved. Afterwards, adjust the pH to 5.5 ± 0.05.
Phase B: Combine all ingredients and heat to 75-80 °C. Then add phase B to phase A while homogenising.
Add phase C to the finished formulation and homogenise.

Appearance: White low viscous emulsion
Stability: No separation after centrifugation (4000 rpm, 30 min), stable for 3 months at room temperature and 40 °C
Microbiological stability: proven

Phase A: Allow the Cosphaderm® Diols + Hydrolyzed Jojoba Esters to pre-dissolve. Then add to the water and add the thickeners while stirring. Mix until everything is homogeneous and heat to 85-90°C.
Phase B: Combine all ingredients of phase B separately and heat to 90°C.
Add phase B to phase A while stirring. Homogenise while cooling.
Phase C: Add phase C and mix/homogenise.
Adjust pH value to 6.80 ± 0.05.

Appearance: Black, high viscous emulsion
pH: 6.8 ± 0.05
Stability: No separation after centrifugation (4000 rpm, 30 min), stable for 3 months at room temperature and 40 °C
Microbiological stability: proven