FORMULATIONS

Phase A: Combine all ingredients of phase A and stir until everything is completely dissolved. Heat to 75 °C.
Phase B: Combine all ingredients and heat to 75 °C. Add then phase B to phase A under strong stirring and homogenise.
Phase C: Add phase C to the formulation and stir.
Adjust the pH to 5.5 ± 0.05.

Appearance: White, high viscous emulsion
pH: 5.5 ± 0.05
Stability: No separation after centrifugation (4000 rpm, 30 min), stable for 3 months at room temperature and 40 °C
Microbiological stability: proven

Phase A: Combine all ingredients of phase A and stir until everything is completely dissolved. Heat to 75 °C.
Phase B: Combine all ingredients and heat to 75 °C. Add then phase B to phase A under strong stirring and homogenise.
Phase C: Add phase C to the formulation and stir.
Adjust the pH to 5.5 ± 0.05.

Appearance: Yellowish green, high viscous emulsion
pH: 5.5 ± 0.05
Stability: No separation after centrifugation (4000 rpm, 30 min), stable for 3 months at room temperature and 40 °C
Microbiological stability: proven

Phase A: Combine all ingredients of phase A and stir until everything is completely dissolved. Heat to 70-75°C.
Phase B: Combine all ingredients of phase B and heat to 70-75°C.
Add phase B to phase A while stirring.
Phase C: Add phase C under 40 °C and homogenise.
Adjust the pH to 5.5 ± 0.05.

Appearance: White high viscous cream
pH: 5.5 ± 0.05
Stability: No separation after centrifugation (4000 rpm, 30 min), stable for 3 months at room temperature and 40 °C
Microbiological stability: proven

Phase A: Dissolve Phase A at 40°C.
Phase B: Combine all ingredients of phase B separately and add to phase A under stirring.
Adjust pH to 5.5 ± 0.05 if necessary.

Appearance: Transparent, low viscous serum
pH: 5.5 ± 0.05
Stability: No separation after centrifugation (4000 rpm, 30 min), stable for 3 months at room temperature and 40 °C
Microbiological stability: proven

Phase A: Combine all ingredients of phase A.
Phase B: Combine all ingredients of phase B separately and add to phase A under stirring.
Phase C: Add phase C to A/B and stir until everything is completely dissolved.
Adjust pH to 5.5 ± 0.05.

Appearance: Transparent, low viscous serum
pH: 5.5 ± 0.05
Stability: No separation after centrifugation (4000 rpm, 30 min), stable for 3 months at room temperature and 40 °C
Microbiological stability: proven

Phase A: Combine all ingredients of phase A and stir until everything is dissolved.
Phase B: Premix all ingredients of phase B and add to phase A while stirring.
Phase C: Combine the ingredients of phase C and add them to the formulation. Stir until everything is homogeneous.
Adjust pH to 5.5 ± 0.05.

Appearance: Clear, transparent, low viscous gel
pH: 5.5 ± 0.05
Stability: No separation after centrifugation (4000 rpm, 30 min), stable for 3 months at room temperature and 40 °C
Microbiological stability: proven

Phase A: Combine all ingredients of phase A and stir until everything is completely dissolved.
Phase B: Add phase B to phase A under stirring.
Adjust the pH to 6.0 ± 0.05 to thicken the formulation.

Appearance: Transparent, clear, viscous gel
pH: 6.0 ± 0.05
Stability: No separation after centrifugation (4000 rpm, 30 min), stable for 3 months at room temperature and 40 °C
Microbiological stability: proven

Phase A: Combine all ingredients of phase A.
Phase B: Prepare phase B and slowly add to phase A under stirring. Continue stirring until everything is completely dissolved.
Adjust pH to 5.5 ± 0.05.

Appearance: Transparent, clear liquid
pH: 5.5 ± 0.05
Stability: No separation after centrifugation (4000 rpm, 30 min), stable for 3 months at room temperature and 40 °C
Microbiological stability: proven

Phase A: Combine all ingredients of phase A and stir until everything is completely dissolved.
Phase B: Add phase B to phase A.
Phase C: Add phase C and stir until everything is completely dissolved.
Adjust pH to 6.5 ± 0.05 if necessary.

Appearance: Transparent, low viscous serum
pH: 6.5 ± 0.05
Stability: No separation after centrifugation (4000 rpm, 30 min), stable for 3 months at room temperature and 40 °C
Microbiological stability: proven

Phase A: Combine all ingredients of phase A and stir until everything is completely dissolved. Heat to 75 °C.
Phase B: Combine all ingredients and heat to 75 °C. Add then phase B to phase A under strong stirring and homogenise.
Phase C: Add phase C to the formulation and stir.
Adjust the pH to 5.5 ± 0.05.

Appearance: White, fluid emulsion
pH: 5.5 ± 0.05
Stability: No separation after centrifugation (4000 rpm, 30 min), stable for 3 months at room temperature and 40 °C
Microbiological stability: proven

Phase A: Combine all ingredients of phase A and stir until everything is completely dissolved. Heat to 75 °C.
Phase B: Combine all ingredients and heat to 75 °C. Add then phase B to phase A under strong stirring and homogenise.
Phase C: Add phase C to the formulation and stir.
Adjust the pH to 5.5 ± 0.05.

Appearance: White, high viscous emulsion
pH: 5.5 ± 0.05
Stability: No separation after centrifugation (4000 rpm, 30 min), stable for 3 months at room temperature and 40 °C
Microbiological stability: proven

Phase A: Combine all ingredients of phase A and stir until everything is completely dissolved.
Phase B: Combine all ingredients of phase B.
Heat both phases separately to 75-80 °C. Add phase B to A while stirring and then homogenise.
Adjust the pH to 5.5 ± 0.05.

Appearance: White, viscous gel cream
pH: 5.5 ± 0.05
Stability: No separation after centrifugation (4000 rpm, 30 min), stable for 3 months at room temperature and 40 °C
Microbiological stability: proven

Phase A: Mix all ingredients together.
Phase B: Slowly add Cosphaderm® X 34 and Aristoflex® AVC under stirring to phase A. Continue stirring until complete dissolution. Then heat to 80 °C.
Phase C: Mix all ingredients and heat to 80 °C. Add phase C to phase A+B and homogenise.
Phase D: Add Cosphaderm® Dicapo below 40 °C under stirring.
Adjust the pH to 5.5 ± 0.05.

Appearance: Light beige, shiny, viscous emulsion
pH: 5.5 ± 0.05
Stability: No separation after centrifugation (4000 rpm, 30 min), stable for 3 months at room temperature and 40 °C
Microbiological stability: proven

Phase A: Combine all ingredients of phase A.
Phase B: Disperse Cosphaderm® KG in glycerol and add it to phase A. Stir until completely dissolved.
Phase C: Add phase C and stir until everything is homogeneous.
Phase D: Prepare phase D and melt at 50 °C, then cool down to room temperature.
Add phase D to the water phase and homogenise.
Adjust pH to 5.5 ± 0.05.

Appearance: Shiny, viscous emulsion
pH: 5.5 ± 0.05
Stability: No separation after centrifugation (4000 rpm, 30 min), stable for 3 months at room temperature and 40 °C
Microbiological stability: proven

Phase A: Prepare phase A and stir until everything is completely dissolved. Adjust pH value to 5.5.
Phase B: Add Cosphaderm® Sodium pAS natural to phase A under stirring.
Phase C: Prepare phase C and add it to phase A/B. Homogenise.
Adjust pH value to 5.5 ± 0.05.

Appearance: Beige, shiny, low viscous emulsion
pH: 5.5 ± 0.05
Stability: No separation after centrifugation (4000 rpm, 30 min), stable for 3 months at room temperature and 40 °C
Microbiological stability: proven

Phase A: Prepare phase A. Raise the pH to 10 to dissolve Cosphaderm® pAS natural and stir until everything is completely dissolved. Afterwards, adjust the pH to 5.5 ± 0.05 by adding Citric Acid.
Phase B: Prepare phase B and add it to phase A while stirring. Stir until everything is completely dissolved.
Phase C: Prepare phase C and add it to phase A/B. Homogenise.
Adjust pH value to 5.5 ± 0.05.

Appearance: Beige, shiny, low viscous emulsion
pH: 5.5 ± 0.05
Stability: No separation after centrifugation (4000 rpm, 30 min), stable for 3 months at room temperature and 40 °C
Microbiological stability: proven

Phase A: Prepare phase A. Raise the pH to 10 to dissolve Cosphaderm® AS natural and stir until everything is completely dissolved. Afterwards, adjust the pH to 5.5 ± 0.05 by adding Citric Acid.
Phase B: Prepare phase B and add it to phase A while stirring. Stir until everything is completely dissolved.
Phase C: Prepare phase C and add it to phase A/B. Homogenise.
Adjust pH value to 5.5 ± 0.05.

Appearance: Beige, shiny, low viscous emulsion
pH: 5.5 ± 0.05
Stability: No separation after centrifugation (4000 rpm, 30 min), stable for 3 months at room temperature and 40 °C
Microbiological stability: proven

Phase A: Combine all ingredients of phase A and raise the pH to 11 to dissolve the cinnamic acid completely. Afterwards, adjust the pH to 5.5 ± 0.05 by adding Citric Acid.
Phase B: Add phase B to phase A while stirring. Stir until everything is completely dissolved.
Phase C: Prepare phase C and heat both phases separately to 75 °C.
Add phase C to phase A/B under stirring and homogenise the mixture.
Phase D: Add phase D to the formulation.
Adjust the pH to 5.5 ± 0.05.

Appearance: Black, creamy paste with small exfoliants
pH: 5.5 ± 0.05
Stability: No separation after centrifugation (4000 rpm, 30 min), stable for 3 months at room temperature and 40 °C
Microbiological stability: proven

Phase A: Combine all ingredients of phase A and stir until everything is completely dissolved. Heat to 70-75 °C.
Phase B: Combine all ingredients of phase B and heat to 75°C. Phase C is added to the oil phase just before emulsion is formed.
Add phase B+C to the water phase while stirring. Homogenise at 40°C.
Adjust the pH to 5.5 ± 0.05.

Appearance: White, viscous cream
pH: 5.5 ± 0.05
Stability: No separation after centrifugation (4000 rpm, 30 min), stable for 3 months at room temperature and 40 °C
Microbiological stability: proven

Phase A: Combine all ingredients of phase A.
Phase B: Prepare phase B and slowly add to phase A under stirring. Continue stirring until everything is completely dissolved.
Adjust pH to 5.5 ± 0.05.

Appearance: Transparent, low viscous serum
pH: 5.5 ± 0.05
Stability: No separation after centrifugation (4000 rpm, 30 min), stable for 3 months at room temperature and 40 °C
Microbiological stability: proven

Phase A: Combine all ingredients of phase A and stir until everything is completely dissolved.
Phase B: Add all ingredients and to phase A and homogenise.
Adjust the pH to 5.5 ± 0.05.
Heat the mixture to its boiling point and keep this temperature for 2 – 3 minutes (Warning: Lecithins are heat sensitive. Therefore, the process of heating should be kept to a minimum!).
Quickly pour the hot mixture into a casting mould and let it cool.

Appearance: White to off-white, elastic jelly patch
pH: 5.5 ± 0.05
Stability: Stable for 3 months at room temperature and 40 °C
Microbiological stability: proven

Phase A: Combine all ingredients.
Phase B: Prepare phase B and slowly add to phase A under stirring. Continue stirring until everything is completely dissolved.
Adjust pH to 6.5 ± 0.05 if necessary.

Appearance: Translucent, low viscous serum
pH: 6.5 ± 0.05
Stability: No separation after centrifugation (4000 rpm, 30 min), stable for 3 months at room temperature and 40 °C
Microbiological stability: proven

Phase A: Prepare phase A.
Phase B: Pre-disperse phase B and add to the water phase while stirring. Stir until everything is completely dissolved.
Adjust the pH to 5.5 – 6.0 ± 0.05.
Heat the mixture to its boiling point and keep this temperature for 2 – 3 minutes.
Quickly pour the hot mixture into a casting mould and let it cool.

Appearance: Transparent or coloured, elastic jelly patch
pH: 5.5 – 6.0 ± 0.05
Stability: Stable for 3 months at room temperature and 40 °C
Microbiological stability: proven

Phase A: Prepare phase A.
Phase B: Pre-disperse phase B and add to the water phase while stirring. Stir until everything is completely dissolved.
Adjust the pH to 5.5 – 6.0 ± 0.05.
Heat the mixture to 80-90°C and keep this temperature for 2 – 3 minutes.
Quickly pour the hot mixture into moulds and let it cool down.

Appearance: Transparent or coloured, elastic jelly patch
pH: 5.5 – 6.0 ± 0.05
Stability: Stable for 3 months at room temperature and 40 °C
Microbiological stability: proven

Phase A: Combine all ingredients of phase A and raise the pH to 10 to dissolve Cosphaderm® pAS natural. Stir until everything is completely dissolved. Afterwards, adjust the pH to 6.0 ±0.2 by adding Citric Acid.
Phase B: Add all ingredients of phase B to phase A and adjust the pH to 5.5 ± 0.05.
Phase C: Combine all ingredients and heat to 80 °C. Then add phase A/B to phase C while homogenising.
Add phase D to the finished formulation and homogenise.

Appearance: White, slightly beige, high viscous cream
pH: 5.5 ± 0.05
Stability: No separation after centrifugation (4000 rpm, 30 min), stable for 3 months at room temperature and 40 °C
Microbiological stability: proven

Phase A: Combine all ingredients of phase A and stir until everything is completely dissolved. Heat to 70-75 °C.
Phase B: Combine all ingredients and heat to 75 °C. Add then phase B to phase A under strong stirring and homogenise.
Phase C: Add phase C below 40 °C.
Adjust the pH to 5.5 ± 0.05.

Appearance: White viscous fluid
pH: 5.5 ± 0.05
Stability: No separation after centrifugation (4000 rpm, 30 min), stable for 3 months at room temperature and 40 °C
Microbiological stability: proven

Phase A: Prepare phase A and stir until everything is completely dissolved. Adjust pH value to 5.5.
Phase B: Add Cosphaderm® Sodium pAS natural to phase A under stirring.
Phase C: Prepare phase C and homogenise for 5 minutes with high performance disperser (stator/rotor) at max. speed.
Add phase C to phase A+B in small steps under stirring.
Adjust pH value to 5.5 ± 0.05.

Appearance: Shiny liquid emulsion
pH: 5.5 ± 0.05
Stability: no separation after centrifugation (4000 rpm, 30 min)

Phase A: Combine all ingredients of phase A and stir until everything is completely dissolved.
Phase B: Slowly add phase B to A while stirring.
Phase C: Mix all ingredients of phase C and add to phase A+B while stirring.
Adjust the pH to 5.0 ± 0.05.

Appearance: Transparent, low viscous serum
pH: 5.0 ± 0.05
Stability: No separation after centrifugation (4000 rpm, 30 min), stable for 3 months at room temperature and 40 °C
Microbiological stability: proven

Phase A: Combine all ingredients of phase A and stir until everything is dissolved.
Phase B: Prepare all ingredients of phase B.
Afterwards combine phase A and B while stirring slowly until a homogeneous gel is formed.
Adjust pH to 5.5 ± 0.05.

Appearance: Yellowish, slightly turbid, viscous gel
pH: 5.5 ± 0.05
Stability: No separation after centrifugation (4000 rpm, 30 min), stable for 3 months at room temperature and 40 °C
Microbiological stability: proven

Phase A: Combine all ingredients and dissolve Phase A at 40°C.
Phase B: Add phase B to phase A and adjust the pH to 5.0 – 5.5.
Phase C: Add phase C to phase A/B under soft stirring.
Phase D: Dissolve Cosphaderm® Magnolia Extract 98 in Cosphaderm® Propanediol natural and Cosphaderm® TOM. Add phase D to phase A/B/C under stirring.
Adjust the pH to 5.0 ± 0.05.

Appearance: Yellowish, translucent gel
pH: 5.0 ± 0.05
Stability: No separation after centrifugation (4000 rpm, 30 min), stable for 3 months at room temperature and 40 °C
Microbiological stability: proven

Phase A: Combine all ingredients of phase A and stir slowly until everything is completely dissolved.
Phase B: Combine all ingredients of phase B.
Add phase B to phase A under stirring with the propeller stirrer.
Adjust the pH to 5.5 ± 0.05.

Appearance: Milky, white viscous gel
pH: 5.5 ± 0.05
Stability: No separation after centrifugation (4000 rpm, 30 min), stable for 3 months at room temperature and 40 °C
Microbiological stability: proven

Phase A: Combine all ingredients of phase A and stir until everything is completely dissolved.
Phase B: Add Cosphaderm® SF-75H to phase A and let it soak for 10-20 minutes. Then heat phase A+B to 70 °C.
Phase C: Combine all ingredients of phase C and heat to 70 °C. Add then phase C to phase A+B under
strong stirring and homogenise the formulation.
Adjust the pH to 5.0 ± 0.05.

Appearance: Light beige gel cream
pH: 5.0 ± 0.05
Stability: No separation after centrifugation (4000 rpm, 30 min), stable for 3 months at room temperature and 40 °C
Microbiological stability: proven

Phase A: Combine all ingredients of phase A.
Phase B: Disperse Cosphaderm® KG in glycerol and add phase B to phase A. Stir until everything is dissolved.
Phase C: Add phase B to phase A/B.
Adjust the pH to 4.8 – 5.0.

Appearance: Turbid, high viscous gel
pH: 4.8 – 5.0
Stability: No separation after centrifugation (4000 rpm, 30 min), stable for 3 months at room temperature and 40 °C
Microbiological stability: proven

Phase A: Disperse Cosphaderm® X 34 in glycerol and add demin. water. Stir until everything is dissolved.
Phase B: Add phase B to phase A.
Adjust the pH to 4.8 – 5.0.

Appearance: Transparent, high viscous gel
pH: 4.8 – 5.0
Stability: No separation after centrifugation (4000 rpm, 30 min), stable for 3 months at room temperature and 40 °C
Microbiological stability: proven

Phase A: Combine all ingredients of phase A.
Phase B: Add phase B to A carefully to avoid foaming.
Adjust the pH to 5.5 ± 0.05.

Appearance: Transparent liquid solution
pH: 5.5 ± 0.05
Stability: No separation after centrifugation (4000 rpm, 30 min), stable for 3 months at room temperature and 40 °C
Microbiological stability: proven

Phase A: Combine all ingredients of phase A and stir until everything is completely dissolved.
Phase B: Combine all ingredients of phase B.
Heat both phases separately to 70-75 °C and add phase B to A very slowly while homogenising.
Phase C: Cool down to 40°C and add Phase C.

Appearance: Slightly yellowish high viscous gel
Stability: stable for 3 months at room temperature and 40 °C
Microbiological stability: proven (Water activity value less than 0.75)

Phase A: Combine water and Cosphagard® SA natural and raise the pH value to 10 – 11. Stir until complete dissolution. Afterwards lower the pH to approximately 6.
Phase B: Add phase B to phase A and stir until everything is completely dissolved. Heat to 70 °C.
Phase C: Combine all ingredients of phase C and heat to 70 °C.
Add phase C to A+B while stirring. Homogenise at 40°C.
Phase D: Add Cosphaderm® TOM to the emulsion.
Adjust pH to 6.0 ± 0.05.

Appearance: Light beige lotion
pH: 6.0 ± 0.05
Stability: No separation after centrifugation (4000 rpm, 30 min), stable for 3 months at room temperature and 40 °C
Microbiological stability: proven

Phase A: Combine all ingredients of phase A and stir until everything is dissolved. Heat to 65 °C.
Phase B: Prepare all ingredients of phase B and heat to 65 °C.
Add phase B to phase A under stirring. Homogenise.
Adjust the pH to 5.5 ± 0.05 if necessary.

Appearance: White viscous gel cream
pH: 5.5 ± 0.05
Stability: No separation after centrifugation (4000 rpm, 30 min), stable for 3 months at room temperature and 40 °C
Microbiological stability: proven

Phase A: Mix all ingredients except Cosphaderm® CHA. Add Cosphaderm® CHA and Stir phase A until complete dissolution.
Phase B: Slowly add Cosphaderm® X 34 to phase A while stirring.
Phase C: Mix phase C and add to phase A+B while carefully stirring to prevent foaming.
Adjust the pH to 5.5 ± 0.05.

Appearance: Transparent viscous gel
pH: 5.5 ± 0.05
Stability: No separation after centrifugation (4000 rpm, 30 min), stable for 3 months at room temperature and 40 °C
Microbiological stability: proven

Phase A: Add Cosphaderm® X soft to the water and stir until it’s completely dissolved.
Phase B: Add phase B in small steps to phase A while stirring at 1500rpm.
Phase C: Add phase C in small steps to phase A+B while stirring at 1500rpm.
Adjust the pH to 7.0 ± 0.05.

Appearance: translucent, viscous gel
pH: 7.0 ± 0.05

Tested against bacteria according to DIN EN 1500, 1276, 1650.

Phase A: Prepare phase A and stir until dispersed.
Phase B: Slowly add the water to phase A under stirring and stir until complete dissolution.
If wanted, add heat-proof colour.
Phase C: Prepare phase C, adjust the pH to 5.5 ± 0.05 and set aside.
Heat phase A+B to its boiling point and keep this temperature for 2 – 3 min.
Add phase C to the hot phase A+B. Continue stirring until everything is combined.
Quickly pour the warm mixture into moulds and let it cool down.

Appearance: Clear, solid, elastic jelly
pH: 5.5 – 6.5
Stability: stable for 3 months at room temperature and 40 °C
Microbiological stability: proven

Phase A: Combine all ingredients of phase A and stir until dispersed.
Phase B: Prepare phase B and lower the pH to ~ 5.5.
Add phase C and phase A to phase B.
Adjust the pH to 5.5 ± 0.05.

Heat the prepared solution to 80 – 90 °C and stir at this temperature for 2 – 3 min.
Quickly pour the warm mixture into moulds and let it cool down.

Appearance: Clear, solid, elastic jelly
pH: 5.5 ± 0.05
Stability: stable for 3 months at room temperature and 40 °C
Microbiological stability: proven

Phase A: Combine all ingredients of phase A and stir until Cosphaderm® X 34 and Cosphaderm® Sodium Hyaluronate are dispersed.
Phase B: Add phase B to phase A.
Phase C: Add phase C to phase A+B under stirring.
Adjust the pH to 5.5 ± 0.05.

Appearance: Transparent, clear gel
pH: 5.5 ± 0.05
Stability: No separation after centrifugation (4000 rpm, 30 min), stable for 3 months at room temperature and 40 °C
Microbiological stability: proven

Phase A: Combine all ingredients and stir until everything is completely dissolved.
Phase B: Combine phase B separately and add phase B to phase A under soft stirring. Stir until both phases are mixed.
Phace C: Add phenylpropanol to phase A+B. Adjust th pH to 5.5 ± 0.05.

Appearance: Transparent, viscous liquid
pH: 5.5 ± 0.05
Stability: No separation after centrifugation (4000 rpm, 30 min), stable for 3 months at room temperature and 40 °C
Microbiological stability: proven

Phase A: Combine all ingredients and stir until Cosphaderm® X 34 is completely dissolved.
Phase B: Combine phase B and add phase B to phase A under slow stirring.
Phase C: Add phase C to phase A+B to thicken the formulation.
Adjust the pH to 5.5 ± 0.05.

Appearance: Milky, white vicous gel
pH: 5.5 ± 0.05
Stability: No separation after centrifugation (4000 rpm, 30 min), stable for 3 months at room temperature and 40 °C
Microbiological stability: proven

Phase A: Combine all ingredients of phase A. Raise the pH to 11 to dissolve Cosphagard® SA natural. When everything is dissolved, lower the pH back to 5-6 again.
Phase B: Add Cosphaderm® X 34 to phase A and stir until everything is completely dissolved.
Phase C: Combine all ingredients of phase C separately. Add then phase C to phase A+B.
Phase D: Add phase D to the finished formulation.
Adjust the pH to 5.5 ± 0.05.

Appearance: Translucent gel with small peeling beads
pH: 5.5 ± 0.05
Stability: No separation after centrifugation (4000 rpm, 30 min), stable for 3 months at room temperature and 40 °C
Microbiological stability: proven

Phase A: Combine all ingredients of phase A and stir until everything is completely dissolved.
Phase B: Add phase B to A carefully to avoid foaming.
Adjust the pH to 5.5 ± 0.05.
Phase C: Add phase C to the final formulation while stirring.

Appearance: Transparent gel with small peeling beads
pH: 5.5 ± 0.05
Stability: No separation after centrifugation (4000 rpm, 30 min), stable for 3 months at room temperature and 40 °C
Microbiological stability: proven

Phase A: Combine ingredients and stir until Cosphaderm® Magnolia Extract 98 is dissolved.
Phase B: Prepare phase B and add to phase A under stirring. Heat the mixture to 50 °C.
Phase C: Slowly add phase C into A+B and stir until complete dissolution.
Phase D: Prepare phase D and add it to phase A+B+C under stirring.
Phase E: Add phase E to the mixture and stir until everything is homogenous.
Phase F: Prepare phase F and add it to the finished formulation.
Adjust the pH to 7.0 ± 0.05.

Appearance: Milky-white paste
pH: 7.0 ± 0.05
Stability: No separation after centrifugation (4000 rpm, 30 min), stable for 3 months at room temperature and 40 °C
Microbiological stability: proven

Phase A: Combine all ingredients of phase A. Pre-dissolve Cosphaderm® X 34 in glycerol and it to phase A. Stir until completely dissolved.
PhaseB: Add phase B to phase A.
Phase C: Pre-dissolve menthol in Cosphaderm® Propanediol natural and then add to phase A+B with the other raw materials.
Phase D: Add phase D and mix homogeneously.
Adjust pH value to 6.8-7.0.

Appearance: Transparent, high viscous gel
pH: 6.8 – 7.0
Stability: No separation after centrifugation (4000 rpm, 30 min), stable for 3 months at room temperature and 40 °C
Microbiological stability: proven