FORMULIERUNGEN

Manufacturing Process
Phase A: Disperse the thickeners in glycerol and Cosphaderm® Propanediol natural.
Phase B: Add demin. water and stir until everything is dissolved.
Phase C: Add phase C to A/B.
Adjust the pH to 5.5 ± 0.05.

Specification
Appearance: Translucent gel
pH: 5.5 ± 0.05
Stability: Microbiological stability proven, no separation after centrifugation (4000 rpm, 30 min)

Manufacturing Process
Phase A: Mix phase A and stir until everything is completely dissolved.
Phase B: Add phase B to phase A and stir until dispersed.
Phase C: Slowly add phase C to phase A+B and stir until complete dissolution.
Phase D: Mix all ingredients of phase D and heat phase A+B+C and D separately to 80 °C.
Add phase D slowly to phase A+B+C while stirring.
Phase E: Add Panthenol to the finished formulation (below 40 °C).
Adjust the pH to 5.5 ± 0.05.

Specification
Appearance: Shiny, fluid emulsion
pH: 5.5 ± 0.05
Stability: Microbiological stability proven, no separation after centrifugation (4000 rpm, 30 min)

Manufacturing Process
Phase A: Prepare phase A and stir until complete dissolution.
Phase B: Prepare phase B and heat to 50 °C until everything is melted. Let the mixture cool down to room temperature.
Add phase B to phase A and homogenise for 3 minutes.
Adjust the pH to 5.5 ± 0.05.

Specification
Appearance: White, shiny emulsion
pH: 5.5 ± 0.05
Stability: Microbiological stability proven, no separation after centrifugation (4000 rpm, 30 min)

Manufacturing Process
This formulation can be prepared at room temperature.
Phase A: Combine all ingredients.
Phase B: Prepare phase B and slowly add to phase A under stirring. Continue stirring for approx. 15 min
at 700 – 1000 rpm until complete dissolution.
Adjust pH to 6.5 ± 0.05 if necessary.

Specification
Appearance: Translucent serum
pH: 6.5 ± 0.05
Stability: Microbiological stability proven, no separation after centrifugation (4000 rpm, 30 min)

Manufacturing Process
Phase A: Prepare phase A and stir until dispersed.
Phase B: Slowly add the water to phase A under stirring and stir until complete dissolution.
Phase C: Prepare phase C and stir for 10 minutes. Add phase C to phase A+B and adjust pH
to 5.5 – 6.0 ± 0.05.
Heat the mixture to its boiling point and keep this temperature for 2 – 3 minutes.
Quickly pour the hot mixture into a casting mould and let it cool.

Specification
Appearance: Translucent or coloured, elastic gel
pH: 5.5 – 6.0 ± 0.05
Stability: Microbiological stability proven, no separation after centrifugation (4000 rpm, 30 min)

Manufacturing Process
Phase A: Combine all ingredients of phase A and stir until complete dissolution.
Adjust the pH value to 5.5 ± 0.05.
Phase B: Prepare phase B in a separate beaker.
Add phase B to phase A without stirring and pour mixture into spray flask.

Specification
Appearance: Two-phase system with oil phase on top of translucent water phase
pH: 5.5 ± 0.05
Stability: Microbiological stability proven

MANUFACTURING PROCESS
Phase A: Combine all ingredients of phase A and stir until everything is completely dissolved.
Phase B: Slowly add phase B to A while stirring.
Phase C: Mix all ingredients of phase C and add to phase A+B while stirring.
Adjust the pH to 5.0 ± 0.05.

SPECIFICATION
Appearance: Clear solution
pH: 5.0 ± 0.05
Stability: Microbiological stability proven, no separation after centrifugation (4000 rpm, 30 min)

Manufacturing Process
Phase A: Combine all ingredients of phase A and stir until everything is dissolved.
Phase B: Slowly add phase B to phase A under stirring. Stir until complete dissolution.
Adjust pH to 5.5 ± 0.05 and heat phase A and B to 70 °C.
Phase C: Combine all ingredients and heat phase C to 70 °C. Add then phase C to phase A and B under
strong stirring and homogenise the formulation.
Adjust pH to 5.2 ± 0.05.

Specification
Appearance: Slightly yellowish gel cream
pH: 5.2 ± 0.05
Stability: Microbiological stability proven, no separation after centrifugation (4000 rpm, 30 min)

Manufacturing Process
Phase A: Combine all ingredients of phase A.
Phase B: Add phase B to phase A while stirring and stir until everything is completely dissolved.
Phase C: Prepare phase C and add to phase A+B under slow stirring to prevent foaming.
Adjust pH to 5.5 ± 0.05.

Specification
Appearance: Transparent gel
pH: 5.5 ± 0.05
Stability: Microbiological stability proven, no separation after centrifugation (4000 rpm, 30 min)

Manufacturing Process
Phase A: Mix all ingredients except Cosphaderm® CHA. Add Cosphaderm® CHA while stirring, then
heat mixture to 70 °C. Stir phase A until complete dissolution.
Phase B: Slowly add Cosphaderm® X 34 to phase A while stirring.
Phase C: Mix phase C and add to phase A+B while carefully stirring to prevent foaming.
Adjust the pH to 5.5 ± 0.05.

Specification
Appearance: Transparent gel
pH: 5.5 ± 0.05
Stability: Microbiological stability proven, no separation after centrifugation (4000 rpm, 30 min)

Manufacturing Process
Phase A: Prepare phase A and stir until dispersed.
Phase B: Slowly add the water to phase A under stirring and stir until complete dissolution.
If wanted, add heat-proof colour.
Phase C: Prepare phase C, adjust the pH to 5.5 ± 0.05 and set aside.
Heat phase A+B to its boiling point and keep this temperature for 2 – 3 min.
Add phase C to the hot phase A+B. Continue stirring until everything is combined.
Quickly pour the warm mixture into moulds and let it cool down.

Specification
Appearance: Clear, solid, elastic jelly
pH: 5.5 – 6.5
Stability: Microbiological stability proven, no separation after centrifugation (4000 rpm, 30 min)

Manufacturing Process
Phase A: Combine ingredients and stir until Cosphaderm® Magnolia Extract 98 is dissolved.
Phase B: Prepare phase B and add to phase A under stirring. Heat the mixture to 50 °C.
Phase C: Slowly add phase C into A+B and stir until complete dissolution.
Phase D: Prepare phase D and add it to phase A+B+C under stirring.
Phase E: Add phase E to the mixture and stir for 10 minutes at 1000 rpm.
Phase F: Prepare phase F and add it to the finished formulation. Adjust the pH to 7.0 ± 0.05.

Specification
Appearance: Milky-white paste
pH: 7.0 ± 0.05
Stability: Microbiological stability proven, no separation after centrifugation (4000 rpm, 30 min)

Manufacturing Process
Phase A: Combine all ingredients of phase A. Slowly add Cosphaderm® X 34 to phase A and stir until completely dissolved.
Phase B: Combine all ingredients of phase B. Heat both phases separately to 80-82 °C.
Add then phase B to phase A under strong stirring and homogenise the formulation.
Adjust pH to 5.5 ± 0.05.

Specification
Appearance: Shiny, white cream
pH: 5.5 ± 0.05
Stability: Microbiological stability proven, no separation after centrifugation (4000 rpm, 30 min)

Manufacturing Process
Phase A: Combine all ingredients of phase A and stir until completely dissolved.
Phase B: Prepare phase B and separately heat phase A and phase B to 80 °C. Add phase B to phase A while stirring.
Phase C+D: Add phase C and D below 40 °C.
Adjust pH to 5.5 ± 0.05.

Specification
Appearance: Slightly yellowish cream
pH: 5.5 ± 0.05
Stability: Microbiological stability proven, no separation after centrifugation (4000 rpm, 30 min)

Manufacturing Process
Phase A: Combine all ingredients of phase A.
Phase B: Add phase B to phase A while stirring and stir until everything is completely dissolved.
Phase C: Prepare phase C and add to phase A+B under slow stirring to prevent foaming.
Adjust pH to 5.5 ± 0.05.

Specification
Appearance: Transparent gel
pH: 5.5 ± 0.05
Stability: Microbiological stability proven, no separation after centrifugation (4000 rpm, 30 min)