FORMULIERUNGEN

Phase A: Combine all ingredients of phase A. Raise the pH to 11 to dissolve Cosphagard® SA natural. When everything is dissolved, lower the pH back to 4-5 again.
Phase B: Combine Glycerin, Cosphaderm® X 34 and Cosphaderm® Sodium Hyaluronate high and stir until the powder is wetted. Then add it to phase A.
Phase C: Add phase C under stirring.
Adjust the pH to 4.0 ± 0.05.

Appearance: Transparent, semi-viscous gel
pH: 4.0 ± 0.05
Stability: No separation after centrifugation (4000 rpm, 30 min), stable for 3 months at room temperature and 40 °C
Microbiological stability: proven

Phase A: Combine all ingredients of phase A. Raise the pH to 11 to dissolve Cosphagard® SA natural completely.
Phase B: Add phase B and lower the pH to 4.0 ± 0.05.

Appearance: Clear, liquid solution
pH: 4.0 ± 0.05
Stability: No separation after centrifugation (4000 rpm, 30 min), stable for 3 months at room temperature and 40 °C
Microbiological stability: proven

Phase A: Combine the ingredients of phase A. Raise the pH to 11 to dissolve Cosphagard® SA natural. When everything is dissolved, lower the pH back to 4-5 again.
Phase B: Add all ingredients from phase B one after another.
Adjust the pH to 4.0 ± 0.05.

Appearance: Transparent, low viscous solution
pH: 4.0 ± 0.05
Stability: No separation after centrifugation (4000 rpm, 30 min), stable for 3 months at room temperature and 40 °C
Microbiological stability: proven

Phase A: Combine all ingredients of phase A. Heat phase A to 40 °C.Raise the pH to 11 to dissolve Cosphagard® SA natural.
Phase B: Add phase B to A and stir until Cosphaderm® X 34 is completely dissolved.
Phase C: Add phase C under stirring.
Phase D: Add phase D to thicken the formulation.
Adjust the pH to 4.5 ± 0.05.

Appearance: translucent, yellowish gel
pH: 4.5 ± 0.05
Stability: No separation after centrifugation (4000 rpm, 30 min), stable for 3 months at room temperature and 40 °C
Microbiological stability: proven

Phase A: Combine all ingredients of phase A. Heat phase A to 40 °C.Raise the pH to 11 to dissolve Cosphagard® SA natural and Cosphaderm® pAS natural.
Phase B: Add phase B to A and stir until Cosphaderm® X 34 is completely dissolved.
Phase C: Add phase C under stirring.
Phase D: Add phase D to thicken the formulation.
Adjust the pH to 4.5 ± 0.05.

Appearance: translucent, yellowish gel
pH: 4.5 ± 0.05
Stability: No separation after centrifugation (4000 rpm, 30 min), stable for 3 months at room temperature and 40 °C
Microbiological stability: proven

Phase A: Combine all ingredients of phase A. Heat phase A to 40 °C.Raise the pH to 11 to dissolve Cosphagard® SA natural and Cosphaderm® AS.
Phase B: Add phase B to A and stir until Cosphaderm® X 34 is completely dissolved.
Phase C: Add phase C under stirring.
Phase D: Add phase D to thicken the formulation.
Adjust the pH to 4.5 ± 0.05.

Appearance: translucent, yellowish gel
pH: 4.5 ± 0.05
Stability: No separation after centrifugation (4000 rpm, 30 min), stable for 3 months at room temperature and 40 °C
Microbiological stability: proven

Phase A: Combine water and Cosphagard® SA natural and raise the pH value to 10 – 11. Stir until complete dissolution. Afterwards lower the pH to approximately 6.
Phase B: Add phase B to phase A and stir until everything is completely dissolved. Heat to 70 °C.
Phase C: Combine all ingredients of phase C and heat to 70 °C.
Add phase C to A+B while stirring. Homogenise at 40°C.
Phase D: Add Cosphaderm® TOM to the emulsion.
Adjust pH to 6.0 ± 0.05.

Appearance: Light beige lotion
pH: 6.0 ± 0.05
Stability: No separation after centrifugation (4000 rpm, 30 min), stable for 3 months at room temperature and 40 °C
Microbiological stability: proven

Phase A: Combine all ingredients of phase A. Raise the pH to 11 to dissolve Cosphagard® SA natural. When everything is dissolved, lower the pH back to 5-6 again.
Phase B: Add Cosphaderm® X 34 to phase A and stir until everything is completely dissolved.
Phase C: Combine all ingredients of phase C separately. Add then phase C to phase A+B.
Phase D: Add phase D to the finished formulation.
Adjust the pH to 5.5 ± 0.05.

Appearance: Translucent gel with small peeling beads
pH: 5.5 ± 0.05
Stability: No separation after centrifugation (4000 rpm, 30 min), stable for 3 months at room temperature and 40 °C
Microbiological stability: proven