FORMULATIONS

Manufacturing Process
Phase A: Mix phase A and stir until everything is completely dissolved.
Phase B: Add phase B to phase A and stir until dispersed.
Phase C: Slowly add phase C to phase A+B and stir until complete dissolution.
Phase D: Mix all ingredients of phase D and heat phase A+B+C and D separately to 80 °C.
Add phase D slowly to phase A+B+C while stirring.
Phase E: Add Panthenol to the finished formulation (below 40 °C).
Adjust the pH to 5.5 ± 0.05.

Specification
Appearance: Shiny, viscous emulsion
pH: 5.5 ± 0.05
Stability: Microbiological stability proven, no separation after centrifugation (4000 rpm, 30 min)

Manufacturing Process
Phase A: Prepare phase A and stir at 2000 rpm until complete dissolution.
Phase B: Prepare phase B and heat to 50 °C until everything is melted. Let the mixture cool down to
room temperature.
Phase C: Prepare phase C and stir for 10 min at 800 rpm.
Add phase C to phase B and stir at 2000 rpm to emulsify both phases.
Add phase A to phase B+C and homogenise for 3 minutes.
Adjust the pH to 5.5 ± 0.05.

Specification
Appearance: White, shiny emulsion
pH: 5.5 ± 0.05
Stability: Microbiological stability proven, no separation after centrifugation (4000 rpm, 30 min)

Manufacturing Process
This formulation can be prepared at room temperature.
Phase A: Combine all ingredients.
Phase B: Prepare phase B and slowly add to phase A under stirring. Continue stirring for approx. 15 min
at 700 – 1000 rpm until complete dissolution.
Adjust pH to 6.5 ± 0.05 if necessary.

Specification
Appearance: Translucent serum
pH: 6.5 ± 0.05
Stability: Microbiological stability proven, no separation after centrifugation (4000 rpm, 30 min)

Manufacturing Process
Phase A: Combine all ingredients of phase A and mix with a stirring rod, then set aside.
Phase B: Add Cosphaderm® CA natural, witch hazel water, allantoin and aloe vera powder to the water
and increase the pH value to 9 – 10. Stir until the powder has dissolved completely. Afterwards, add
Cosphaderm® LA-T to the mixture.
Add phase B to phase A and stir until a slightly viscous gel is formed.
Adjust pH to 5.5 ± 0.05.

Specification
Appearance: Yellowish, clear, slightly viscous gel
pH: 5.5 ± 0.05
Stability: Microbiological stability proven, no separation after centrifugation (4000 rpm, 30 min)

Manufacturing Process
This formulation can be prepared at room temperature.
Phase A: Mix all ingredients of phase A under stirring.
Phase B: Mix all ingredients of phase B under stirring. Add phase A into phase B and homogenise until
everything is dissolved. Adjust the pH to 6.5 ± 0.05.

Specification
Appearance: White cream
pH: 6.5 ± 0.05
Stability: Microbiological stability proven, no separation after centrifugation (4000 rpm, 30 min)