MANUFACTURING PROCESS Phase A: Combine the ingredients of phase A. Raise the pH to 11 to dissolve Cosphagard® SA natural. When everything is dissolved, lower the pH back to 4-5 again. Phase B: Add all ingredients from phase B one after another. Adjust the pH to 4.0 +_ 0.05. SPECIFICATION Appearance: Clear solution pH: 4.0 +_ 0.05 Stability: Microbiological stability proven, no separation after centrhas not

MANUFACTURING PROCESS Phase A: Combine all ingredients of phase A and stir until everything is completely dissolved. Phase B: Add Cosphaderm® SF-75H to phase A and let it soak for 10-20 minutes. Then heat phase A+B to 70 °C. Phase C: Combine all ingredients of phase C and heat to 70 °C. Add then phase C to phase A+B under strong stirring and homogenise the formulation. Adjust the pH to 5.0 +_ 0.05. has not