MANUFACTURING PROCESS Phase A: Combine the ingredients of phase A. Raise the pH to 11 to dissolve Cosphagard® SA natural. When everything is dissolved, lower the pH back to 4-5 again. Phase B: Add all ingredients from phase B one after another. Adjust the pH to 4.0 ± 0.05. SPECIFICATION Appearance: Clear solution pH: 4.0 ± 0.05 Stability: Microbiological stability proven, no separation after centrhas not

Manufacturing Process Phase A: Add all ingredients of phase A into a beaker and stir until caffeine and allantoin are completely dissolved. Phase B: Add phase B to phase A while stirring vigorous. Stir until no clumps are left. Adjust pH to 5.5 +_ 0.05. Specification Appearance: Transparent, clear, slightly viscous liquid pH: 5.5 +_ 0.05 Stability: Microbiological stability proven, no separation afthas not